The COM Add-ins menu option is not available by default. You need to add it to the menu bar by using the Customize feature.
Now you can click on Com add-ins from the Tools pull-down menu. Click on it and you will see the following window:

Here you can see a list of COM add-ins that are installed. By highlighting an add-in you can see the location of the file and the load behavior. If there was a problem loading the add-in there will be a brief description of the problem here.
All add-ins with a check mark in the box are currently loaded. You can Uncheck an add-in to temporarily disable it (it will remain in this list, so you can easily re-enable it), or remove it completely by highlighting the add-in and clicking on Remove.